Accession Number:

AD0749846

Title:

Calcium Flux in Intact Platelets.

Descriptive Note:

Final rept. 1 Mar-31 Aug 72,

Corporate Author:

BOSTON UNIV MASS

Personal Author(s):

Report Date:

1972-10-05

Pagination or Media Count:

6.0

Abstract:

It is conceivable that alteration of platelet control mechanisms for regulating Ca flux may be important to the maintainance of homeostasis, the promotion of hemostasis and the induction of thrombosis. Many investigators have reported on the similarity of the platelet release reaction to secretory processes and the requirement for Ca is needed in both activities. It is reasonable to postulate that some mechanism is required to maintain a low level of intra-cellular calcium until the stimulus for release occurs. The calcium uptake activity of platelet membrane fractions may be an in vitro expression of a calcium pump in the intact cell. Author

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE