Accession Number:

AD0747793

Title:

Anticholenergic Influences upon Habituation to Electrical Brain Stimulation,

Descriptive Note:

Corporate Author:

TEXAS TECH UNIV LUBBOCK CENTER OF BIOTECHNOLOGY AND HUMAN PERFORMANCE

Personal Author(s):

Report Date:

1972-01-01

Pagination or Media Count:

10.0

Abstract:

Habituation has been defined as a response decrement produced by repeated or continuous stimulation Harris 1943. Cain and Carlson 1971 have demonstrated that a response induced by electrical brain stimulation EBS can habituate. Carlton 1963 suggested that the physiological basis of habituation was accumulation of acetylcholine at central cholenergic synapses and that the effects of this accumulation could be blocked by anticholenergic drugs such as scopolamine. The present experiment was designed to test Carltons hypothesis by determining the effect of scopolamine upon habituation of EBS-induced running. Author

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE