Accession Number:

AD0743536

Title:

Interrelation of Systemic and Cellular Responses to Acute and Chronic Hypoxia.

Descriptive Note:

Final rept. 1 Jan 63-31 Dec 70,

Corporate Author:

NORTH CAROLINA UNIV CHAPEL HILL

Personal Author(s):

Report Date:

1971-11-04

Pagination or Media Count:

58.0

Abstract:

A number of separate, though interrelated projects are described in this report. They are grouped into two major categories - 1 the effects of hypoxia on cell metabolism, and 2 the effects of hypoxia on behavior. One of the major objectives was a study of certain features of the process of acclimation to simulated high altitude. This included a the effects of altitude acclimation on cellular metabolic and behavioral responses to acute hypoxia, b the effects of altitude acclimation on one of the enzymes important to anaerobic metabolism latic dehydrogenase and on the relative vascularity of brain, heart and skeletal muscle, c the adaptive value of two of the prominent changes observed at altitude hyperventilation and polycythemia, and d an attempt to determine the stimulus responsible for the increased vascularity of organs in altitude-acclimated animals. Author

Subject Categories:

  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE