Accession Number:

AD0743082

Title:

The Rapid Diagnosis of Acute Respiratory Disease Due to Adenovirus: Preparation and Standardization of Fluorescent Antibody Reagents

Descriptive Note:

Medical research progress rept. no. 6

Corporate Author:

NAVAL MEDICAL FIELD RESEARCH LAB CAMP LEJEUNE NC

Report Date:

1972-05-01

Pagination or Media Count:

12.0

Abstract:

Fluorescent antibody reagents were prepared for the rapid diagnosis of acute respiratory disease caused by adenovirus in a military population. Methods are described for the preparation of high-titered antisera in rabbits, fractionation of globulins from the serum, conjugation with fluorescein isothiocyanate, and sorption to remove nonspecific staining. Fluorescein-tagged antisera were specific at diluations of 120 to 130.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE