Features Peculiar to Nicotinic Acid Metabolism in Acute Respiratory Diseases
FORT DETRICK FREDERICK MD FREDERICK
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During sporadic acute respiratory sicknesses, tonsillitis, and pneumonia, stereotypic deviations in the metabolism of nicotinic acid, including decreased level of pyridine nucleotides in whole blood and erythrocytes and in raised spontaneous removal in the urine of N1-methylnicotinamid and its 6-pyridon were observed. Expressivity and duration of metabolic shifts of nicotinic acid is found in direct relation to the intensity and duration of inflamatory changes of the breathing apparatus. To compensate for the losses of nicotinic acid in the acute phase of the disease, addition of the vitamin in the food in a daily dose of 4080mg, granulated, was ordered.
- Medicine and Medical Research