Accession Number:

AD0738116

Title:

Synthesis of Spirocyclic Derivatives Related to the Butyrophenone Neuroleptics.

Descriptive Note:

Technical rept. 6 Jan 69-2 Mar 70,

Corporate Author:

EDGEWOOD ARSENAL MD

Personal Author(s):

Report Date:

1972-02-01

Pagination or Media Count:

22.0

Abstract:

A number of analogs related to haloperidol were synthesized and submitted for biological evaluation. In the course of the studies, two novel synthetic procedures were developed The preparation of ketones by addition of acid chlorides to organocopper compounds and The two-step preparation of secondary amines from tertiary benzyl amines having a divalent sulfur atom in the molecule. Author

Subject Categories:

  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE