Accession Number:

AD0734824

Title:

Blood Cholinesterase Variation in Sheep under Different Holding Conditions.

Descriptive Note:

Technical rept. Sep 69-Mar 71,

Corporate Author:

EDGEWOOD ARSENAL MD

Personal Author(s):

Report Date:

1971-12-01

Pagination or Media Count:

17.0

Abstract:

A monitoring program, including the use of domestic sheep as sentries for open-air tests of anticholinesterase agents, was developed in the event emergency circumstances would dictate that this testing program be resumed. The sheep would be placed in monitor pens on the periphery of the test grid after each test, and blood cholinesterase ChE activity would be measured periodically. This report presents a method for measuring ChE in erythrocytes and plasma of sheep and describes a baseline study in which sheep selected as indicator animals were placed in monitor baseline study in which sheep selected as indicator animals were placed in monitor pens to evaluate their physiological responses, especially ChE variations. Significant depressions of erythrocyte and plasma ChE occurred in some animals. These depressions were incorporated into estimates of normal ChE variation for each sentry sheep. Author

Subject Categories:

  • Animal Husbandry and Veterinary Medicine
  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE