Radiation Effects in Man: Manifestations and Therapeutic Efforts
Annual rept. 1 May 1970-30 Apr 1971
CINCINNATI UNIV OH COLL OF MEDICINE
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The goal of the program has been to obtain new information regarding the patho-physiologic, psychologic, immunologic, hematologic, and biochemical effects of total- and partial-body irradiation in human beings. The patients are irradiated, all of whom have inoperable, metastatic carcinoma but are in relatively good health, provide the opportunity to study multiple facets of the effects of radiation in man rather than in experimental animal. Many laboratories have discovered that the extrapolation of results from laboratory animals to man to be fraught with error. The data contained in this report will suggest several potential biological dosimeters previously considered to be of some value have not fulfilled this expectation. Several new biological dosimeters are under evaluation.