Characterization of Tissue Ingrowth into Porous Bioceramics.
Technical rept. no. 1, May-Sep 71,
CLEMSON UNIV S C DIV OF INTERDISCIPLINARY STUDIES
Pagination or Media Count:
Bone ingrowth and tissue reaction to 316 inch diameter cylindrical pellets of two porous test ceramics porcelain and titania and a previously investigated porous material calcium aluminate were observed for 6 and 12 weeks. Partial sections of porcelain and titania 14 to 12 of the diameter of the midshaft of the femus and one inch long were implanted to test the ceramic materials in a stress situation. A basic characterization of the ceramic material was made in relation to fracture stress, strain to fracture, apparent bulk density, pore size, and interconnection pore size distribution. The results revealed the lack of any adverse tissue reaction to the ceramic implants. Mineralized bone was found penetrating the porous structure of the pellets of the two test materials to a depth of 1750 to 1800 microns with an average of 1300 to 1400 microns in 12 weeks. Analysis of the reference material demonstrated mineralized bone ingrowth up to 900 microns with an average of 500 microns in 12 weeks however, the bone was separated from the calcium aluminate by a 50 micron seam of unmineralized bone osteoid. Author
- Medicine and Medical Research