The Effect of Interferon on Viremia in Arbovirus Infection
FORT DETRICK FREDERICK MD FREDERICK
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The paper presents the results of a study of viremia in mice experimentally infected with Venezuelan equine encephalomyelitis virus. It was shown that higher sensitivity to infection by this virus in suckling mice than in adult mice is reflected in higher viremia. It was established that the highest levels of viremia coincide with maximum interferon content in the blood. In absolute terms interferon production in suckling mice was lower than in adult mice, but virus titers in the blood of the suckling mice was considerably higher than in adult mice. The work discusses theories on the influence of interferon on neurovirus infection in the viremia phase.
- Medicine and Medical Research