Accession Number:

AD0733827

Title:

The Effect of Interferon on Viremia in Arbovirus Infection

Descriptive Note:

Technical Report

Corporate Author:

FORT DETRICK FREDERICK MD FREDERICK

Personal Author(s):

Report Date:

1971-12-15

Pagination or Media Count:

12.0

Abstract:

The paper presents the results of a study of viremia in mice experimentally infected with Venezuelan equine encephalomyelitis virus. It was shown that higher sensitivity to infection by this virus in suckling mice than in adult mice is reflected in higher viremia. It was established that the highest levels of viremia coincide with maximum interferon content in the blood. In absolute terms interferon production in suckling mice was lower than in adult mice, but virus titers in the blood of the suckling mice was considerably higher than in adult mice. The work discusses theories on the influence of interferon on neurovirus infection in the viremia phase.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE