Accession Number:

AD0733571

Title:

A Behavioural and Neuropathological Study of the Sequelae of Profound Hypoxia,

Descriptive Note:

Corporate Author:

FLYING PERSONNEL RESEARCH COMMITTEE LONDON (ENGLAND)

Report Date:

1971-01-01

Pagination or Media Count:

20.0

Abstract:

Eighteen monkeys Macaca mulatta, trained on tasks of visual discrimination and spatial alternation, were exposed in air to a steady ambient pressure of 160 mm Hg equivalent to an altitude of 37.500 ft with a calculated inspired oxygen tension of 24 mm Hg. In 7 animals there was neuropathological evidence of brain damage and examination revealed two patterns of cellular loss. Disturbances of visual discrimination and spatial alternation behaviour were observed only in animals with brain damage and were consistent with previous studies on the sequelae of restricted surgical lesions. There was no evidence of behavioural disturbances in animals without brain damage. Author

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE