Accession Number:

AD0733165

Title:

The Beneficial Effects of Postirradiation Treatment with Cobaltous Chloride on the Development of Nuclear Damage in Thymocytes, Erythropoiesis, and the Survival of Mice,

Descriptive Note:

Corporate Author:

NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) DIV OF BIOLOGY

Personal Author(s):

Report Date:

1971-03-29

Pagination or Media Count:

7.0

Abstract:

Cobaltous chloride injected subcutaneously into mic immediately after irradiation decreases the number of cells with pyknotic nuclei appearing in the lymphocyte population of the thymus. In vitro studies show that the presence of cobaltous chloride in the incubating medium immediately after irradiation again lowers the subsequent appearance of cells with pyknotic nuclei. A subcutaneous injection of cobaltous chloride into mice immediately after irradiation also increases both erythropoietic recovery and survival. Author

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE