Accession Number:

AD0731132

Title:

Heartworm and Hookworm Disease in Military Dogs: Chemoprophylaxis with Diethylcarbamazine and Strylpyridinium.

Descriptive Note:

Final rept. Oct 68-Jun 71,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1971-09-01

Pagination or Media Count:

20.0

Abstract:

Effective chemoprophylaxis of hookworm and heartworm infections was achieved by feeding military working dogs low-level dosages of styrylpyridinium and diethylcarbamazine daily. Ten groups of military working dogs located in the United States, Japan, the Philippines, Vietnam, and Thailand received daily dosages of the drugs for extended periods of up to 27 months. The incidence of hookworm infections at those bases where all the dogs received the drugs was reduced to less than 1 within 30 days and remained so throughout the study. At bases where both medicated and nonmedicated groups were maintained, the incidence of hookworm infection was statistically lower in the medicated animals than in the nonmedicated animals. Heartworm disease control was equally effective, as none of the 36 medicated dogs shipped en masse to the test bases from Lackland Air Force Base, Tex., developed heartworms whereas 17 of 62 control animals maintained at the same bases developed the disease. At one base where dogs previously assigned were utilized, 19 of 58 control animals developed heartworm disease while only 2 of 23 medicated animals developed the disease. Contraindications to low-level dosage with the drugs were not observed. Author

Subject Categories:

  • Animal Husbandry and Veterinary Medicine
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE