Accession Number:

AD0730813

Title:

Plasma Catecholamines and the Effects of Adrenergic Beta Receptor Blockade on Cardiovascular and Mental Reactions during Emotional Stress,

Descriptive Note:

Corporate Author:

KAROLINSKA INSTITUTET STOCKHOLM (SWEDEN)

Report Date:

1967-01-01

Pagination or Media Count:

10.0

Abstract:

Cardiovascular reactions during emotional stress were studied in ten subjects five labile hypertensives, four alcoholics, one healthy subject. The reactions observed included a very marked fall in forearm vascular resistance marked tachycardia, and moderate rises in systolic and diastolic pressures. Subsequent to adrenergic beta-receptor blockade with I.V. propranolol, the same stressors produced similar blood pressure responses, but the changes in heart rate and vascular resistance were markedly reduced. The data from the very limited number of experiments to date indicate that labile hypertensive subjects react in a more pronounced manner to stress-inducing agents than do chronic alcoholics with respect to rise in arterial pressure, elevated heart rate and forearm vasodilation. The autonomic findings and their relations to plasma levels of adrenaline and noradrenaline as well as reported subjective reactions are discussed. Author

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE