Accession Number:

AD0729973

Title:

Mechanisms of Hemolysis.

Descriptive Note:

Annual summary rept.,

Corporate Author:

CALIFORNIA UNIV SAN DIEGO LA JOLLA SCHOOL OF MEDICINE

Personal Author(s):

• Bernstein,Eugene F.

Report Date:

1971-08-01

Pagination or Media Count:

46.0

Abstract:

Wall or surface interaction trauma did not result in striking or significant changes or erythrocyte ATP concentration, or 2,3-diphosphoglycerate concentration. The phosphate concentration of the suspending medium has a critical effect upon the maintenance of both ATP and 2,3-diphosphoglycerate concentration in the erythrocyte, and, secondarily, upon shifts in the oxyhemoglobin dissociation curve. A suitable device for selective shear stress damage has been constructed, and is presently in operation. Author

Descriptors:

• (*HEMOLYSIS
• CELL WALL)
• SHEAR STRESSES
• ERYTHROCYTES
• ADENOSINE PHOSPHATES
• HEMOGLOBIN

Subject Categories:

• Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE