The Behavioral Basis of Action of Tranquilizers,
WESTERN MICHIGAN UNIV KALAMAZOO
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The discovery that a single dose of chlorpromazine to an individual subject can produce opposite influences on two distinctly different types of behavior occurring at different times and places is reported. The findings suggest the general principle that the behavioral effect of tranquilizer agents is to shift an organisms response tendency from post-event aggressivity toward pre-event anticipatory and orienting motor reactions, the necessary precursors of rewarded performance. It is probable that the therapeutic efficacy of the tranquilizer is the result of such a process.