Accession Number:

AD0725690

Title:

Leptospiral Ultrasonic Polyvalent Depot-Vaccine (Leptsspkrsznaya Ultrazeiuksvaya Pslieyalentnaya Depo-Vakchina),

Descriptive Note:

Corporate Author:

ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA

Personal Author(s):

• Samedov,A. S.
• Kosideeva,S. G.

Report Date:

1971-05-19

Pagination or Media Count:

10.0

Abstract:

A new polyvalent leptospiral depot-vaccine prepared by the method of ultrasonic destruction of a concentrated suspension of leptospira with subsequent standardization and deposition with aluminum hydroxide was evaluated. The vaccine contains antigens isolated from 5 serotypes of leptospirae grippotyphosa, hebdomadis, canicola, pomona and tarassovi and protects from infection with 8 types of leptospira infection grippotyphosa, hebdomadis, saxkoebing, canicola, icterohaemorrhagiae A and AB, pomona and tarassovi. After a single immunization in a dose of 1.5 ml rabbits remained immune for 1 year. Single vaccination with a crude vaccine protected rabbits from infection with a virulent culture in a dose of 4-15 D1m. Author

Descriptors:

• *LEPTOSPIRA
• *VACCINES
• USSR
• BACTERIA
• DISEASES
• IMMUNITY
• ANTIGENS
• ANTIBODIES
• DOSAGE
• EFFICIENCY
• PREPARATION
• EXPERIMENTAL DATA
• RABBITS

Subject Categories:

• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE