Odor Sensing Cell Ultrastructure by Electron Microscopy.
HONEYWELL INC HOPKINS MINN CORPORATE RESEARCH CENTER
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The report is divided into five sections including the effects of octanol and ascorbic acid on the ATPase activities in rabbit olfactory epithelium, the initial studies on immobilized enzymes, the completion of the observations on the regeneration of olfactory cells and centriole migration during regeneration and normal development, and the developments in applying radioautography to olfactory studies. Octanol was found to stimulate the Na-K ATPase activity from olfactory tissue but to inhibit the same activity from brain. Ascorbic acid caused inhibition of Na-K ATPase activity under conditions in which it could readily oxidize to dehydroascorbic acid. Glucose oxidase and urease were immobilized in acrylamide gel which shows good possibilities of being developed into sensing systems. Regeneration of olfactory epithelium may be in the form of olfactory cells or ciliated columnar cells or a mixture, but they all appear to originate from the Bowmans glands. The incidence of centriole migration in variously aged animals and in adult regeneration tissue supports a hypothesis that olfactory cell development persists well into the adult life of the animal. Author
- Anatomy and Physiology