Accession Number:

AD0719994

Title:

Primary Structure of alpha-Lytic Protease: a Bacterial Homologue of the Pancreatic Serine Proteases,

Descriptive Note:

Corporate Author:

NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) BIOCHEMISTRY LAB

Report Date:

1970-07-21

Pagination or Media Count:

5.0

Abstract:

Comparison of the amino-acid sequence of the bacterial alpha-lytic protease wit the mammalian pancreatic proteases shows homologies in the regions of the N-terminus, the single histidine, an aspartic acid residue, the active serine, and in the positions of the three disulphide bridges. The partial sequence of a trypsin-like enzyme from Streptomyces griseus provides further evidence for divergent evolution of this class of enzymes from a common ancestral gene. Author

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE