Accession Number:

AD0718317

Title:

Monkey Performance After Partial Body Irradiation: Dose Relationships,

Descriptive Note:

Corporate Author:

ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD

Personal Author(s):

Report Date:

1970-11-01

Pagination or Media Count:

27.0

Abstract:

Forty-one male and thirty female monkeys Macaca mulatta were trained by shock avoidance conditioning to work a simultaneous visual discrimination problem. Trained subjects received either 2500, 4500, or 10,000 rads midline tissue doses of pulsed mixed gamma-neutron radiation. Within each dose group some animals were head shielded, some were trunk shielded, and some were not shielded. The midline tissue dose behind the shield at the middle of the head or chest was less than 8 percent of the midline tissue dose to the same point without the shield in place. All unshielded monkeys and many shielded monkeys suffered early incapacitation after irradiation. Within dose groups at 2500 rads and at 10,000 rads, the incapacitation was about equally severe for unshielded, head-shielded, and trunk-shielded subjects however, it generally was more severe at 10,000 rads than in similarly irradiated monkeys that received 2500 rads. At 4500 rads, early incapacitation did not occur in all shielded subjects, and, if it did occur in a shielded monkey, recovery occurred sooner than in most unshielded subjects at 4500 rads. There was some indication that, generally, males could perform better than females after irradiation. Author

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE