Permeability of the Skin to Gases
Annual rept. no. 1, 1 Jan 1969-1 Jun 1970
MASSACHUSETTS GENERAL HOSPITAL BOSTON
Pagination or Media Count:
The report presents a study of the permeability of human skin epidermis and stratum corneum to vapors and gases. Physical measurements include the determination of the solubility of homologous series of organic vapors, alkanes, alcohols, etc. ... in stratum corneum the permeability of these substances through epidermis and the measurement of gas-tissue sorption rates and equilibria. Primary emphasis is placed upon the measurement of fundamental physical constants characteristic of the tissue and relevant to diffusion. The effect of hydration of the permeability of gases and vapors is studied. The mechanism of diffusion of gases through dry stratum corneum is discussed and compared with diffusion through hydrated tissue.
- Chemical, Biological and Radiological Warfare