Accession Number:

AD0713726

Title:

SOME EFFECTS OF D-AMPHETAMINE ON CARBOHYDRATE METABOLISM AT GROUND LEVEL AND ALTITUDE.

Descriptive Note:

Interim rept. Dec 69-Mar 70,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1970-09-01

Pagination or Media Count:

10.0

Abstract:

Measurement was made of blood glucose, liver glycogen, phosphorylase, and glucose-6-phosphatase in rats treated with d-amphetamine at ground level and at a simulated altitude of 8,000 ft. An increase in blood sugar levels was obtained in drug-treated animals in both environments. Altitude exposure per se also increased blood sugar levels, but the increase was not additive at altitude following drug treatment. Liver glucose-6-phosphatase activity was unaffected by drug or altitude exposure. Glycogen levels were lower in both amphetamine-treated groups, while phosphorylase activity was increased. The response of these two parameters was the same at ground level and at altitude. Author

Subject Categories:

  • Biochemistry
  • Stress Physiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE