Accession Number:

AD0711552

Title:

ANTIGENIC AND BIOLOGICAL CLASSIFICATION OF DENGUE VIRUSES.

Descriptive Note:

Final rept. 1 Nov 66-31 Oct 69,

Corporate Author:

YALE UNIV NEW HAVEN CONN SCHOOL OF MEDICINE

Report Date:

1970-06-01

Pagination or Media Count:

53.0

Abstract:

Dengue viruses are the cause of two distinct diseases, dengue fever DF, a mild and self limited illness and dengue hemorrhagic fever DHF, a severe disease with an appreciable mortality rate. This investigation addressed itself to the hypothesis that two subpopulations of dengue viruses exist, virulent and avirulent, and that the virulence of a dengue infection is correlated with identifiable antigenic markers on the virus. In addition, an attempt was made to evaluate in sub-human primates the hypothesis that a second dengue infection is modified by host factors to result in more severe disease response. Author

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE