Accession Number:

AD0706421

Title:

INHIBITION AND REACTIVATION OF ACETYLCHOLINESTERASE MODIFIED BY REACTION WITH 1,1-DIMETHYL-2-PHENYLAZIRIDINIUM ION,

Descriptive Note:

Corporate Author:

DEFENCE RESEARCH ESTABLISHMENT OTTAWA (ONTARIO)

Personal Author(s):

Report Date:

1969-09-01

Pagination or Media Count:

4.0

Abstract:

The authors previously described the modification of the esteratic activity of acetylcholinesterase by reaction with 1,1-dimethyl-2-phenylaziridinium ion DPA. An increased hydrolysis of indophenyl acetate by this modified cholinesterase DPA-enzyme made it possible to examine its reaction with organophosphorus compounds and preliminary results were described. This work was continued, and the reactivation of phosphorylated DPA-enzyme was investigated. Author

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE