IDENTIFICATION OF PHOTODYNAMIC SYSTEMS IN THE RETINA.
Final scientific rept. 1 Oct 68-30 Jun 69,
SASSARI UNIV (ITALY) INST OF BIOLOGICAL CHEMISTRY AND GENERAL PATHOLOGY
Pagination or Media Count:
The retina lesions caused by light so called solar retinitis is not related to a heat effect due either to the collimation of infra-red rays or to the transformation in heat of visible light by absorption from the pigment layer. Our data on isolated calf retina demonstrated for the first time that light produces an oxygen dependent damage of the retina respiratory enzymes. The present final scientific report refers to the demonstration that a the reciprocity law i x t k i is the intensity of light, and t is the exposure time holds for the photodynamic sensitivity of the retina b the threshold dosage of such a sensitivity is about 200,000 ergsq cm for isolated bovine retina c the chromophores active in producing the damage are in the range of 320-380 nm and 380-500 nm. Author
- Medicine and Medical Research