Accession Number:

AD0701170

Title:

Effect of Lysergic Acid Diethylamide on Escherichia coli, Strain B/r(lambda)

Descriptive Note:

[Technical Report, Technical Report]

Corporate Author:

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Personal Author(s):

• Dowler, Michael J.
• Wolpert , Jack S.

Report Date:

1970-02-01

Pagination or Media Count:

22

Abstract:

The effect of LSD on E. coli was examined as a test system for damage to genetic material. LSD had a dose-dependent effect on bacterial growth rate. This effect was not amplified by the DNA-repair inhibitor caffeine. The lowering of the growth rate by LSD was shown to be completely reversible upon dilution. LSD was shown to cause a dose dependent extension of the growth recovery lag due to UV damage. Caffeine caused a much larger extension of this lag time.

Descriptors:

Subject Categories:

• Biochemistry
• Microbiology

Distribution Statement:

[A, Approved For Public Release]