OBSERVATIONS ON CERTAIN ENDOCRINOLOGICAL RESPONSES OF THE HAMSTER
EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD
Pagination or Media Count:
Some endocrinological responses of the hamster are similar to those of the albino rat however, there are important differences. In the hamster, as in the rat, chemical thyroidectomy effects little or no significant change in the ascorbic acid content of the pituitary gland. The hamster, unlike the rat, shows no significant change in the ascorbic acid content of the adrenal, pituitary, hypothalamus, cerebrum, or liver for a period of up to 15 days following ovariectomy. l-Alanine does not exert a gluconeogenic effect upon the liver of fasted hamsters of either sex, whereas it rapidly replenishes the glycogen stores of fasted rats. Following adrenalectomy, neither hamsters nor rats show any increase in liver glycogen after having ingested l-alanine. Corticosterone is unable to stimulate repletion of liver glycogen in either the normal or adrenalectomized hamster, whereas the closely allied steroid cortisol is very efficacious under these conditions in the rat.
- Anatomy and Physiology