CHEMICAL RANGING AND TRACKING.
Final rept. 27 Dec 67-30 Jan 69,
NORTHWESTERN UNIV EVANSTON ILL DEPT OF BIOLOGICAL SCIENCES
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The vertebrate nose is unrivaled in its sensitivity to a wide range of trace chemical substances occurring in air and water. At present there are no useful, broad spectrum instruments suitable for real time-chemical detection and analysis. Significant advances in understanding the chemical basis of the olfactory receptor membrane and in relating the signalling parameters of nervous activity to receptor stimulation were made during the period of this grant. In addition, a comparative histological study turned up a vertebrate nose with very large receptor cells, which should allow one to monitor cell function with intracellular microelectrodes for the first time. Finally, several methods were developed for using an electrochemical cell as an indicator of the presence of trace contaminants in a flowing stream. Author
- Anatomy and Physiology
- Biomedical Instrumentation and Bioengineering