SERUM AGGLUTINATORS REACTING WITH PEPSIN TREATED GAMMA-GLOBULIN: I. 'NATURALLY OCCURRING' REACTANTS IN THE SERUM OF SUBHUMAN PRIMATES
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
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The sera of subhuman primates were found to contain anti-gamma globulins directed against pepsin revealed antigens of primate immunoglobulin. These reactants were compared to similar antibodies of human serum and showed striking similarities in specificity and immunochemical characteristics. Further, both human and subhuman pepsin agglutinators were widely distributed and autoreactive. Attempts to induce formation of alteration of the titer of these antibodies in monkeys by hyperimmunization were unsuccessful.
- Anatomy and Physiology