Accession Number:

AD0689642

Title:

EFFECTS OF LOCAL ALTERATIONS OF pCO2 AND pH ON CEREBROVASCULAR RESISTANCE IN ISOLATED DOG HEADS,

Descriptive Note:

Corporate Author:

ALBERTA UNIV EDMONTON

Report Date:

1969-01-01

Pagination or Media Count:

5.0

Abstract:

The local effects of graded increases and decreases of paCO2 and pH on cerebral vascular resistance were determined in isolated dog heads. Two preparations were utilized In the first series, a donor dog was included in the extracorporeal circulation to supply blood to the constant flow perfused, decapitate head in the second series, the donor dog was replaced with an oxygenator-reservoir system. Results indicate that the direct effect of increasing paCO2 and decreasing pH is a fall of cerebral vascular resistance and vice versa. Author

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE