Accession Number:

AD0688130

Title:

A RATIONALE FOR THE PREPARATION OF NONTHROMBOGENIC MATERIALS.

Descriptive Note:

Technical rept.,

Corporate Author:

WALTER REED ARMY MEDICAL CENTER WASHINGTON D C ARMY MEDICAL BIOMECHANICAL RESEARCH LAB

Personal Author(s):

Report Date:

1969-04-01

Pagination or Media Count:

11.0

Abstract:

It is postulated that negative charges, per se, are insufficient to impart thromboresistance to a polymer surface. Rather, it is hypothesized that a specific steric array of negative charges is required certain distribution favoring thromboresistance and others either not imparting thromboresistance or, indeed, enhancing the possibility of thrombus formation. The distances between charges required may be a function of whether an intramolecular calcium bridge may be formed. It is proposed that truly neutral surfaces may be more suitable as thromboresistant surfaces. Author

Subject Categories:

  • Biochemistry
  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE