Accession Number:

AD0687692

Title:

SHORT TERM CLINICAL EVALUATION OF A CLAY CONTAINING DENTIFRICE

Descriptive Note:

Interim rept.,

Corporate Author:

NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT

Personal Author(s):

Report Date:

1969-02-12

Pagination or Media Count:

15.0

Abstract:

The causes of gingivitis are almost universally ascribed to the effects of toxic products of the bacterial plaque. One form of control of the disease could therefore include the effective removal of these toxins. A highly absorbing clay dentifrice compound has been developed which appeared promising in laboratory and animal tests. A short term clinical trial was conducted on 433 Submarine School student volunteers. The subjects were assigned at random to one of three groups the test group, the positive control placebo, and the negative control group. The gingival status of each subject was evaluated by standard means before the study and again after ten weeks. No significant benefits were observed from the agent under study. An appreciable degree of aversion to the taste and to the lack of cleaning ability was noted. It is possible that this lack of subject acceptance may have in large part accounted for the negative results.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE