BACTERICIDAL ACTIVITY OF THE BLOOD OF PERSONS VACCINATED WITH VARIOUS TYPHOID AND TYPHOID-PARATYPHOID VACCINES
ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA
Pagination or Media Count:
Changes in various indices of the blood bactericidal reaction were studied in persons immunized with typhoid and typhoid-paratyphoid vaccines of known epidemiological efficacy. No correlation was revealed between the efficacy of the preparations and their capacity to increase the phagocytic activity of leukocytes to O- and Vi-strains of typhoid bacilli, to stimulate the thermostable and thermolabile bactericidal activity of the blood, or to effect the general complementary activity and properdin system indices. Following vaccination, elevation of blood phagocytic activity and properdin content was observed in persons with relatively low indices before immunization, while no corresponding changes were detected in persons with relatively high initial values.
- Anatomy and Physiology