Accession Number:

AD0687197

Title:

COMPLEX IMMUNIZATION OF ANIMALS AGAINST ANTHRAX AND BRUCELLOSIS

Descriptive Note:

Corporate Author:

ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA

Personal Author(s):

Report Date:

1969-04-22

Pagination or Media Count:

9.0

Abstract:

The feasibility of simultaneous immunization of animals against anthrax and brucellosis has been studied in guinea pigs and sheep. Complex vaccination did not suppress the immunobiological reactions characteristic of these infections, and the thermal reaction was more pronounced than upon separate vaccinations. Upon complex vaccination, the periods of appearance, maximal development, and disappearance of the allergic and thermoallergic reactions of anthrax and brucellosis were indistinguishable from those observed after separate immunizations. Simultaneous injection of anthrax and brucellosis antigens not only does not suppress development of allergies to the corresponding diseases, but even somewhat stimulates these processes. Upon controlled infection with a lethal dose of anthrax culture 5.5 months after immunization by the complex method, sheep demonstrated resistance.

Subject Categories:

  • Animal Husbandry and Veterinary Medicine
  • Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE