SELECTION OF RADIATION-RESISTANT ANIMALS.
Rept. for Feb 66-Oct 67,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
Pagination or Media Count:
Rodents were exposed at weekly intervals to an ethanol-saturated air ambient. Body weight was monitored before and after each exposure. Sedation and recovery times were observed. After a rest period of several days the animals were irradiated to a dose level at which a 100 mortality was expected. The postirradiation survival of the rodents was correlated P .05- .01 in preliminary experiments with preirradiation ethanol-induced body weight changes. The weight change-survival relationship was observed in five different species of rodents. The correlation was found to be present for periods of time up to twenty-one days following stress testing. The test may be applicable to animals exposed to a dose range of several hundred roentgens at the dose level producing a high percentage of mortality. No detectable modification of the postirradiation survival time of the stressed animals was observed. Plots of radiation-induced mortality times were made for the five rodent species. Author
- Anatomy and Physiology