Accession Number:

AD0686731

Title:

INSULIN-INHIBITORY FACTOR IN HUMAN BLOOD: ROLE IN THE CHARCOAL RADIOIMMUNOASSAY.

Descriptive Note:

Rept. for Jan-Jun 68,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Report Date:

1968-12-01

Pagination or Media Count:

10.0

Abstract:

The insulin-inhibitory factor in human blood was studied. The results of a recovery study with a single-antibody assay the charcoal radioimmunoassay were compared to those with a two-antibody assay to determine whether inhibition occurred between insulin and the first antibody or between the first and the second antibody. The single-antibody assay did not show an insulin-inhibitory factor, but the two-antibody radioimmunoassay did show an inhibitor. The inhibitor must therefore act between the anti-human gamma globulin antibody and the anti-insulin antibody to block the reaction. The exact nature of the inhibitor is as yet unknown. Author

Subject Categories:

  • Medicine and Medical Research
  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE