Accession Number:

AD0684174

Title:

CONSTRUCTION OF AN INTERNAL THORACIC DUCT FISTULA.

Descriptive Note:

Technical rept.,

Corporate Author:

WILFORD HALL USAF HOSPITAL LACKLAND AFB TEX

Personal Author(s):

Report Date:

1968-12-01

Pagination or Media Count:

18.0

Abstract:

Lymphocyte depletion produces readily apparent immunological defects. The major defect lies in delayed sensitivity response and, if controlled, it can result in a more effective method of immunologic suppression in transplantation. The present study was an attempt to develop a method of establishing chronic internal lymphatic diversion and, thereby, produce lymphopenia without the sequelae of fluid, electrolytic and caloric loss. A modified Absolon thoracic duct fistula was devised and tested in ten dogs. However, the results in the eight technically satisfactory dogs were no better than those of Absolon, and no advantage was observed in renal homotransplantation models. This report describes the technique and examines possible reasons for failure when used by this investigator. Author

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE