A CONTRIBUTION TO THE INVESTIGATION OF BARRIER FIXING MANIFESTATIONS OF IMMUNITY IN DYSENTERY AND CHOLERA
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
The cholera vibrio and Flexners dysenteric bacteria, in a subcutaneous inoculation of white mice, manifest a sharply expressed invasive capacity within a few minutes after inoculation these bacterial species fill the local lymphatic barrier, break through it and penetrate into the internal organs and blood of the animals. The invasive properties of the Shiga bacteria, as compared to the cholera vibriones and Flexners bacteria, are sharply retarded. In a subcutaneous inoculation of mice that were immunized with cholera and Flexner vaccines the corresponding pathogens did not penetrate deeply into the organism and, as a rule, were fixed at the first lymphatic barrier. The data obtained in this investigation opens the door to a systematic study of the antibacterial barrier fixing manifestations of immunity in cholera, and Flexner dysentery.
- Medicine and Medical Research