PREPARATION AND PROPERTIES OF BOVINE, MONKEY, AND RAT GROWTH HORMONES
ARMY BIOLOGICAL LABS FREDERICK MD
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Growth hormones were obtained from bovine, green marmoset, and rat pituitaries by various methods. They were homogeneous based on data from ultracentrifugation and electrophoresis. The somatotropins from the green marmoset and rats have a similar amino acid composition phenylalanine is the N- and C-terminal amino acid of these hormones. The molecular weight of rat and green marmoset STG equals respectively 27,000 and 30,000. In spite of significant differences in the physico-chemical properties, preparations of bovine, monkey, and rat growth hormones exert a similar biological action on hypophysectomized rats.
- Anatomy and Physiology