Accession Number:

AD0681515

Title:

TOXIC HAZARDS RESEARCH UNIT ANNUAL TECHNICAL REPORT: 1968

Descriptive Note:

Rept. no. 4 (Final), Sep 1967-May 1968

Corporate Author:

SYSTEMED CORP DAYTON OH

Personal Author(s):

Report Date:

1968-10-01

Pagination or Media Count:

60.0

Abstract:

The activities of the Toxic Hazards Research Unit THRU for the period of September 1967 through May 1968 are reviewed in this report. The experimental research program was partially curtailed during the first half of this period while major modifications to the Thomas Domes of the Altitude Facility were being completed. The dome modifications, primarily for improved fire safety protection, were required to be complete before experimentation in oxygen enriched environments could be resumed. Additional facilities for toxicity screening of space cabin materials were placed in service and the evaluation of materials has been continued with little evidence of toxicity exhibited by their gas-off products. One cabin material, carboxy nitroso rubber CNR, did exhibit toxic manifestations and its acute toxic effects were investigated in depth. The CNR pyrolysis products formed at 300C were found to be highly toxic and any human exposure to these products should be guarded against. Acute toxicity experiments on monomethylhydrazine and nitrogen trifluoride, including MMH emergency tolerance limits studies were conducted in the Ambient Facilities of the THRU. Investigations on the use of sham exposed dome controls and techniques for determining organ to body weight ratios are reported.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE