Accession Number:

AD0681501

Title:

THE EFFECT OF HIGH CONCENTRATIONS OF CARBON DIOXIDE ON BLOOD SEROTONIN LEVELS IN MAN. CHRONIC HYPERCAPNIA.

Descriptive Note:

Rept. for 17 Nov-7 Dec 67,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1968-09-01

Pagination or Media Count:

14.0

Abstract:

Whole blood serotonin levels in young men were investigated during exposure to a 4 carbon dioxide environment PICO2 29.9 mm. Hg for a 10-day period. No significant change in serotonin levels was found in those men acting as outside controls at ambient 0.03 carbon dioxide, but there was a 34.0 decrease P .01 of serotonin levels in men exposed to 4 carbon dioxide. Exposure to 4 carbon dioxide produced throbbing headaches day 1-2 and nausea day 4-6. Serotonin levels after an initial depression tended to return to control levels during the 4 carbon dioxide exposure period. Observed correlation between carbon dioxide and serotonin suggests that the role of carbon dioxide in control of cerebral circulation may be mediated through serotonin. Author

Subject Categories:

  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE