STUDIES ON NOSEMA (=ENCEPHALITOZOON) CUNICULI INFECTION IN MAN.
Rept. no. 4 (Final), Jun 67-Jun 68,
KEIO UNIV TOKYO (JAPAN) DEPT OF PARASITOLOGY
Pagination or Media Count:
The purpose of the study was to elucidate whether or not man may be infected with Nosema cuniculi, a microsporidian parasite of rodents. For the isolation of this parasite from man, laboratory animals cannot be used without strict controls, because they often have the latent infection. Tissue culture will be the medium of choice, if the parasite grows well in it. HeLa and L cell cultures were tested and the former gave rise to a better growth of the parasite than the latter. The parasite, however, did not appear in the culture unless a large number of the organisms were inoculated. Further studies are necessary before the tissue culture can be used as a tool for the detection. A number of human materials were inoculated into mice which had received the provocation test with endoxan and had been considered to be free of infection. No conclusive evidence of the infection have so far been obtained. Author