THE EFFECT OF LASER ENERGY ON CELLS IN TISSUE CULTURE.
Annual summary rept. no. 1,
PASADENA FOUNDATION FOR MEDICAL RESEARCH CALIF DEPT OF LASER BIOLOGY
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Ruby laser irradiation causes nonpigmented cells to deposit an agent into the surrounding culture medium which can promote RBC agglutination, blood clotting, WBC chemotaxis and stimulation of cell growth. Blue and green laser wavelengths produce mitochondrial swelling in beating rat heart cells. Morphological changes suggest that a toxic substance is lost from these structures, which results in nuclear pycnosis and death of the cell. A variety of drugs were observed to photosensitize individual mitochondria to an argon laser microbeam. These included various forms of tetracycline, DNP, amytal, and NaF. Author