Accession Number:

AD0679698

Title:

VISUAL DISCRIMINATION PERFORMANCE IN THE MONKEY (MACACA MULATTA): A TECHNIQUE AND ASSESSMENT OF 5000 RADS GAMMA-NEUTRON IRRADIATION,

Descriptive Note:

Corporate Author:

ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD

Personal Author(s):

Report Date:

1968-06-01

Pagination or Media Count:

33.0

Abstract:

A study was undertaken to assess the effects of radiation on visual discrimination performance in the monkey Macaca mulatta. Six monkeys were trained to avoid shock by responding to one of two visual stimuli presented simultaneously. Each monkey was irradiated with approximately 5000 rads of gamma-neutron radiation delivered in a millisecond-range pulse. Behavioral data were obtained from 12 hour prior to the pulse and for 2-12 hours afterwards Phase 1. Thereafter, behavioral data were obtained every 4 hours from pulse time Phase 2. Temporary decrements in visual discrimination performance occurred in five out of six monkeys after exposure median interval 2 minutes, 10 seconds. The duration of the decrement varied between 7-12 minutes and 2-12 hours the duration of Phase 1. All monkeys were able to perform visual discriminations at some time after irradiation. Maximum postirradiation performance during Phase 2 sessions occurred on the average at 8 hours postpulse, but ranged from 4 to 20 hours. Survival time varied from approximately 12-12 hours to 51-12 hours. Vomiting occurred in five out of six animals, but did not appear to interfere with effective performance. The results demonstrated a marked variability in the monkeys response to radiation in both performance and survival time. Author

Subject Categories:

  • Psychology
  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE