Accession Number:
AD0679675
Title:
RETARDED IMMUNOLOGICAL RECOVERY IN SUBLETHALLY X-IRRADIATED MICE BY ADDITIONAL THYMIC EXPOSURE. REVERSAL WITH INJECTED MARROW CELLS,
Descriptive Note:
Corporate Author:
NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF
Personal Author(s):
Report Date:
1968-10-24
Pagination or Media Count:
20.0
Abstract:
The role of the intact thymus in recovery of the immune response following a sublethal dose of X radiation was studied. Groups of adult LAF1 mice were exposed to 500 rad of X rays and some of these animals, appropriately lead-shielded, then received an additional 500, 1000, or 2000 rad to the thymic area through a 1.2 cm diameter shield opening. Three criteria of immunological response were employed 1 numbers of Jerne antibody plaque-forming cells PFC in the spleen 2 concentration of antigen-reactive cells ARC 3 rejection time of skin homografts. Author
Descriptors:
Subject Categories:
- Medicine and Medical Research
- Radiobiology