Accession Number:

AD0678906

Title:

THE ISOLATION OF THE BRUCELLOSIS PATHOGEN FROM THE EYES OF GUINEA PIGS FOLLOWING EXTRAOCULAR INFECTION

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Report Date:

1968-07-01

Pagination or Media Count:

11.0

Abstract:

Conclusions of the experiments are the following The bacteriological investigation of conjunctival secretion merits wide usage in the complex laboratory diagnosis of brucellosis infection in the early stages after the infection of man and animals. It is possible to isolate Brucella organisms from the eyes with experimental endogenous brucellosis ailments of the keratoiridocyclite type by means of culturing in artificial nutrient media and infecting the animals in this, as the time from the beginning of the inflammatory process in the eye and from the moment of infection increases, this possibility is lessened. The formation and duration of the resistance of the eye tissue to Brucella contamination are more reliably provided by subcutaneous vaccination with Brucella organisms of strain Br. abortus bovis 19 than by enteral and intranasal vaccination with the same strain.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE