INVESTIGATION OF THE POSSIBILITY OF ORAL IMMUNIZATION OF EXPERIMENTAL ANIMALS WITH THE SMALLPOX VACCINE VIRUS. REPORT I. IMMUNOLOGICAL CHANGES IN THE VACCINATED ANIMALS
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
A live smallpox virus administered perorally to experimental animals monkeys, rabbits and guinea pigs induced immunological changes a rise in the antihemagglutinin titers and virus-neutralizing antibodies. Simultaneously, there was an increase of cutaneous immunity, determined by intracutaneous inoculation of rabbits with the smallpox vaccine, as per Grott.
- Medicine and Medical Research