Accession Number:

AD0678119

Title:

INVESTIGATION OF THE POSSIBILITY OF ORAL IMMUNIZATION OF EXPERIMENTAL ANIMALS WITH THE SMALLPOX VACCINE VIRUS. REPORT I. IMMUNOLOGICAL CHANGES IN THE VACCINATED ANIMALS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Report Date:

1967-11-20

Pagination or Media Count:

6.0

Abstract:

A live smallpox virus administered perorally to experimental animals monkeys, rabbits and guinea pigs induced immunological changes a rise in the antihemagglutinin titers and virus-neutralizing antibodies. Simultaneously, there was an increase of cutaneous immunity, determined by intracutaneous inoculation of rabbits with the smallpox vaccine, as per Grott.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE