Accession Number:

AD0677843

Title:

HYDRATION OF MACROMOLECULES IN THE NATIVE AND DENATURED STATES

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1967-10-26

Pagination or Media Count:

12.0

Abstract:

The question of the reciprocal influence of macromolecules and the water layers adjacent to them is examined. The Kauzmann and Klotz models are compared. Experimental calorimetric findings on macromolecule hydration are cited. The denaturation change of hydration is studied. It is demonstrated that hydration of denatured macromolecules is greater than hydration of native molecules, which speaks in favor of Kauzmanns model.

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE