Accession Number:

AD0677266

Title:

STUDY OF THE ANTIGENIC COMPOSITION OF SOME F. TULARENSIS STRAINS. REPORT 2. COMPARATIVE ANTIGENIC COMPOSITION OF VIRULENT AND AVIRULENT BACTERIA

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1967-11-29

Pagination or Media Count:

8.0

Abstract:

The presence of 12 antigenic components in avirulent strain No 21400 of F. tularensis was demonstrated by the reaction of precipitation in gel. Using the same method 12 antigenic components identical with those of the avirulent strain and an additional one, A antigen, were demonstrated in a virulent No 128 and vaccine No 15 strains. A antigen is situated on the surface in the capsule and in the bacterial cell wall. Large flake agglutination in the presence of tularemia is related to the presence of A antigen in the bacterial cells and of the corresponding A antibodies in the serum. The virulent No 128 and avirulent No 21400 strains have five thermostable and seven thermolabile antigeni components in common, while the virulent strain contains, in addition, thermostable A antigen.

Subject Categories:

  • Microbiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE