Accession Number:

AD0676347

Title:

COMPLEXES OF INFLUENZA VIRUS WITH ORGANIC BASES AND CATIONIC DETERGENTS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1968-09-01

Pagination or Media Count:

11.0

Abstract:

The virus of influenza precipitates from solutions completely only with cationic detergents. Viruses, like higher proteins, form complex compounds with organic bases and cationic detergents. Stability of linkage of carboxyl groups of the virus micelle with organic bases and cationic detergents is not great, and these complexes more or less easily split in physiological solutions of salts. The search for antiviral chemotherapeutic agents must be directed along the road of search for compounds harmless for organisms, possessing cations that are very complex in structure, of high molecular weight, capable to combine stably with the carboxyl groups of the virus.

Subject Categories:

  • Biochemistry
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE